Stem Cells: Culture, Differentiation and Transplantation

Stem Cells are undifferentiated cells that have the potency to regenerate and differentiate into cells of specific lineage. They are classified as oligo potent, pluripotent, totipotent cells based on the different types of cells formed after differentiation. The broader classification includes embryonic stem cells and adult stem cellsMesenchymal stem cell (MSC) is a variant of adult stem cell that gives rise to osteoblast, adipocytes and chondrocytes. MSC transplantation for tissue engineering has grabbed attention due to its immunosuppressive features. It is now in use to regenerate tissues of kidney, liver, heart; bone etc. Stem cell culture forms the base for the tissue engineering approach. A minor change in the culture environment may lead to altered potency of the cells. So special reagents and media are required. Moreover, 3D culture techniques and CRISPR genome editing technology are also in market.

  • Cancer Stem Cells
  • Mesenchymal Stem Cells
  • Stem Cell Therapy
  • Induced Pluripotent Stem cells (IPSC)

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